How does EndoStim work?

GERD and associated symptoms are often caused by a dysfunctional lower esophageal sphincter (LES) valve between the stomach and the esophagus. The EndoStim neurostimulation system delivers mild electrical signals to the LES automatically throughout the day. This gentle stimulation is designed to restore normal function to the LES, and normally cannot be felt by patients.

EndoStim gently stimulates the LES valve to allow it to function normally again – stay closed to prevent reflux, open to allow for food and drink to pass into the stomach.

The EndoStim System

The EndoStim System consists of a neurostimulator (IPG), implantable bipolar lead and wireless external programmer (used in clinic). The IPG delivers stimulation therapy to the LES via the lead. The device battery is expected to last approximately 7 (Gen 2 device) or 10 (Gen 1 device) years under recommended stimulation algorithms.

The IPG and lead are placed through a minimally-invasive laparoscopic procedure. After the procedure, the EndoStim device is programmed wirelessly by a physician. The stimulation therapy can, if needed, be adjusted at future follow-up visits by a physician.

The Procedure

The EndoStim system is placed through a minimally-invasive procedure. Unlike traditional anti-reflux surgery, the EndoStim procedure is designed to preserve the body’s natural anatomy in order to reduce or avoid gastro-intestinal side effects.

- Minimally-invasive procedure of about 1 hour
- 2 small electrodes placed on the lower esophagus
- EndoStim neurostimulator placed under the skin (in the abdomen)
- Quick recovery

Watch the EndoStim Procedure


EndoStim is a clinically-proven, effective therapy with international commercial experience


Important Notice
The EndoStim system is not approved for sale in the US and is limited by US federal law to investigational use only. In the EU and Latin America, EndoStim is not currently commercially available. Information on this website is intended only to provide general information and not as a definitive basis for diagnosis or treatment. Please consult your doctor about your specific condition, contraindications, and possible complications.