How does the EndoStim System work?

GERD and associated symptoms are often caused by a dysfunctional lower esophageal sphincter (LES) valve between the stomach and the esophagus. The EndoStim neurostimulation system delivers mild electrical signals to the LES automatically throughout the day. This gentle stimulation is designed to restore normal function to the LES, and normally cannot be felt by patients.

The EndoStim System gently stimulates the LES valve to allow it to function normally again – stay closed to prevent reflux, open to allow for food and drink to pass into the stomach.

The EndoStim System

The EndoStim System consists of an implantable neurostimulation device and lead placed via a quick, minimally-invasive laparoscopic procedure. The system is designed to provide long-term reflux control by automatically delivering mild electrical signals throughout the day to the patient’s weak or dysfunctional lower esophageal sphincter (LES) muscle (the underlying cause of GERD).

Delivering EndoStim Therapy

The EndoStim System is placed through a minimally-invasive procedure. Unlike traditional anti-reflux surgery, the EndoStim System is designed to preserve the body’s natural anatomy in order to reduce or avoid gastro-intestinal side effects.

- Minimally-invasive procedure of about 1 hour
- 2 small electrodes placed on the lower esophagus
- EndoStim neurostimulator placed under the skin (in the abdomen)
- Quick recovery

Once placed, the EndoStim System delivers stimulation therapy to the LES via the lead. the EndoStim System is programmed wirelessly by a physician using an external handheld controller. The System automatically stimulates the LES to allow it to function normally without any sensation to the patient.

The stimulation therapy can, if needed, be adjusted at future follow-up visits by a physician, and the device battery is expected to last approximately six years under recommended stimulation algorithms.

The EndoStim System has been successfully investigated in multiple independent international studies.

EndoStim is a clinically-proven, effective therapy with international commercial experience

Important Notice

The EndoStim system is not approved for sale in the US and is limited by US federal law to investigational use only. In the EU and Latin America, EndoStim is not currently commercially available. Information on this website is intended only to provide general information and not as a definitive basis for diagnosis or treatment. Please consult your doctor about your specific condition, contraindications, and possible complications.